Custom Protein Expression (CPE) runs gene synthesis, expression, purification and QC in E. coli, yeast, insect and mammalian cells, for Non-GMP research or GMP manufacturing in our GMP-compliant facility. We also produce recombinant antibodies from your sequence in a 12-business-day standard cycle.
Four expression hosts share one six-stage workflow. Every project starts with a pre-project assessment of your sequence, intended use, target amount, purity, endotoxin limits and manufacturing grade.
Choose from full-length human, mouse and rabbit IgG, VHH and scFv formats, or supported bispecific designs. Share your sequence, target quantity and intended application so our technical team can review the production plan and define the delivery specifications.
Routine and GMP projects follow the same broad technical sequence. Controls, records, equipment and quality requirements are selected for the manufacturing route and intended application.
Construct design, gene synthesis and cloning for the selected host.
BL21, Pichia, Sf9 or mammalian host, with expression verification or clone screening.
Expression under conditions chosen for the target.
Recovery and purification suited to the protein, with SEC polishing when needed.
Larger-scale expression and purification, quoted on scale and yield.
PAGE analysis and a COA or study report, plus agreed tests and GMP records.
The stage split differs slightly by host. Each service page lists its own stages and prices.
A GMP program typically requires greater control and documented evidence at each relevant stage, rather than a completely different biochemical expression mechanism.
Laboratory research, assay development and other agreed non-clinical applications. Flexible screening and optimization, with a data summary, research report and COA as agreed.
Production in CPE's own GMP-compliant facility, with controlled production zones, qualified equipment, traceable materials, approved instructions, batch records and quality review appropriate to the regulatory context.
Sterility and endotoxin content are separate product attributes, specified and tested for the intended application. Regulatory suitability is assessed case by case.
Custom Protein Expression (CPE) provides custom recombinant antibody production from your antibody sequence. Our service covers gene synthesis, mammalian expression, purification and quality control for antibody characterization and assay development. The standard production cycle is 12 business days from sequence confirmation, excluding shipping time.
Send your sequence or accession, target quantity, intended application and required grade. CPE reviews feasibility and returns a project-specific plan and quotation.
